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-->   Takashi Nakagawa Last modified date：2024.05.11 Professor / Department of Clinical Medicine Faculty of Medical Sciences 1 Research Interests 2 Current and Past Project 3 Academic Activities 3.1 Books 3.2 Papers 3.3 Presentations 4 Membership in Academic Society 5 Educational Activities Graduate School Department of Medicine and Surgery Graduate School of Medical Sciences Undergraduate School Department of Medicine School of Medicine E-Mail　*Since the e-mail address is not displayed in Internet Explorer, please use another web browser:Google Chrome, safari. Homepage https://kyushu-u.elsevierpure.com/en/persons/takashi-nakagawa　Reseacher Profiling Tool　Kyushu University Pure Phone 092-642-5668 Fax 092-642-5685 Academic Degree M.D./Ph.D. Country of degree conferring institution (Overseas) No Field of Specialization otorhinolaryngology ORCID(Open Researcher and Contributor ID) https://orcid.org/0000-0002-3198-639X Total Priod of education and research career in the foreign country 02years00months Outline Activities ENT clinician, specialized in Otology, Audiology, Skull base surgery, Pediatric hearing disorders and Auditory Physiology Research Research Interests clinical and basic research in temporal bone tumorkeyword : temporal bone, auditory system, cancer1998.01basic and clinical research of temporal bone carcinoma. Estimation and strategy for congenital deafness and acquired deafness in childrenkeyword : congenital deafness, acquired hearing impairment in children2015.12～2026.03. Current and Past Project Development and clinical application of novel hearing device for conductive and mixed hearing impairment. Squamous cell carcinoma of temporal bone is rare and the treatment strategy depends on other head and neck cancers. Since it has specific characteristics, the carcinogenic mechanism may be different from other head and neck cancers, i.e., anatomical or biological factors. We are aiming at an establishment of the treatment strategy based on molecular biological and microanatomical evidences. Academic Activities Books  Show All Books >> 1. 中川 尚志, 末田 尚之, 鍋島一樹, Surgical management of T1 and T2 lesions with outcomes. / Nakagawa T, Sueta T, Nabeshima M．Cholesteatoma and Ear Surgery –an update．Takahashi H edn. (2013, pp. 133-136), Kugler Publications, Amsterdam, 2013.09, We treated 56 patients with squamous cell carcinoma of external auditory canal (EAC) and middle ear. Settings were Kyushu University Hospital from January 1998 to March 2006 and Fukuoka University Hospital from April 2006 to March 2011. Mean age was 65 years (ranged between 41 and 93 years). There were 31 male and 26 female patients. Cases of a follow-up period of more than 12 months were included in the study. Patients who died of the disease were not included. Mean follow-up period was 37 months. Numbers of cases: T1N0 = one; T1N1 = none; T2N0 = 12; T2N1 = three; T3N0 = seven; T3N1 = two; T4N0 = 20; T4N1 = 11. Twenty-nine percent (n = 16) had lymph-node metastasis. The five-year survival rate of T3 and T4 was 89% and 52%, respectively. However, the five-year survival rate of T1 and T2 decreased to 68% and was lower than that of T3. Although treatment strategy was maintained during 12 years, the number of cases of T1 and T2 was roughly three times that of the previous report. Fig. 3 shows details of T1 and T2 cases. Four patients died of the disease in the follow-up period of 16, 18, 18 and 37 months. Markers of epithelial-mesenchymal transition (EMT) in the SCC tumor cells were examined in seven out of 16 cases. Three out of four patients who died of the disease were included in the study. Vimentin was positive and laminin was diffusely stained in all cases.. Papers  Show All Papers >> 1. Imai K, Yamano T, Nishi S, Nishi R, Tanaka H, Tsunoda T, Yoshimoto S, Tanaka A, Hiromatsu K, Shirasawa S, Nakagawa T, Nishi K., Epipharyngeal abrasive therapy (EAT) has potential as a novel method for long COVID treatment., Viruses, https://doi.org/10.3390/v14050907, 14, 907, 2022.01. Presentations  Show All Presentations >> Membership in Academic Society Audiological Society of Japan Facial nerve society of Japan Otological Society of Japan Society of Otorhinolaryngology of Japan Educational Educational Activities Education of medical student and graduate student of medical sciences Unauthorized reprint of the contents of this database is prohibited. Copyright © 2006, Kyushu University. All rights reserved.